What if you couldn’t feel pain — not physical, not even the sharpest injury? That’s the reality for Nathan 'Nate' Caine, the unusual protagonist of Novocaine, a 2025 action-comedy that’s anything but numb. Directed by Dan Berk and Robert Olsen and written by Lars Jacobson, the film stars The Boys actor Jack Quaid as a shy, pain-immune bank employee who suddenly finds himself in a high-stakes rescue mission.
Set in sunny San Diego, Novocaine follows Nate, a quiet man with a rare genetic condition that makes him completely impervious to pain. His world is turned upside down when his charming new co-worker, Sherry Margrave (played by Prey breakout Amber Midthunder), is kidnapped during a violent bank robbery. What starts as a blossoming office romance turns into an all-out action chase, with Nate using his unusual biology as his greatest weapon.
Novocaine was released in theaters on March 14, 2025, and quickly shot to the top of the box office despite tough competition. Thanks to sharp humor, heartfelt performances, and stylized action, it received a 82% critics score on Rotten Tomatoes and sparked buzz across social media.
With a fast-paced story, surprising heart, and a hero who can take a hit better than anyone,this film lands every punch — and sticks with you.
